Thrombus: Medical tests

The index of the potential thrombodynamique (IPT) is a number that allows you to get a clear idea, based on the results of thrombo-elastogram, the strength of a blood clot. In some pathologies (structural hypercoagulability), this test is worth practicing. For specialists, the potential thrombodynamique index is calculated by dividing the value of Emx by that of K. The figures are normal between 5 and 10. When they are above 12 is referred to as structural hypercoagulability, when they are less than 5, it is hypocoagulability structurale.Le test Fearnley, called in English Fearnley's test, is the time of lysis is ie destruction of the clot from the blood that was diluted. Fearnley's test is normally more than three hours.The von Kaulla test developed in 1958 (known in English euglobulin lysis test) is synonymous with time measurement of lysis of euglobulins is a method to measure the capacity of destruction of the clot (fibrinolysis) by the blood through the study of fibrinolysis activators, mainly plasminogen. Activators of fibrinolysis are contained in a variety of proteins: the euglobulins. These are precipitated (metropolitan area) by adding an acid (acidification) and then diluted and coagulated. Inhibitors of fibrinolysis, which is part antiplasmin, will float in the liquid obtained. Usually, the clot of euglobulins is destroyed (lysis) after 3 hours, sometimes more. When you get a dissolution (destruction, lysis) faster, it witnessed a plethora of activators and therefore a tendency to fibrinolysis. We talk about: The role is to prevent the normal formation of the clot. Nevertheless, they are the source of certain diseases. These substances consist of antibodies that is to say a variety of proteins belonging to the immune system (defense system of the body). Some of these antibodies are specific to a clotting factor, factor VIII generally. When they are highlighted in the body it means that there is a deficit in the factor responsible. Other anticoagulants cancel the clotting process by intervening at one time or another clotting (phase). This has led to a more global disruption of the body. This is mainly antiprothrombinases. One of the diseases caused by circulating anticoagulant is the lupus erythematosus. In this case it is the lupus anticoagulant or "lupus anticoagulant" by Conley and Hartmann are responsible for this pathology.